If you want 50% more power than 5.56, there are better choices, they have been on the market longer, and one is a military SBR round used in the Mid East.
.300BO was a market "sharing" concept by AAC to exploit sales of subsonic guns and silencers. They usurped .300 Whisper, which was a niche cartridge and barely moving on the market.
If anything, using it supersonic was returning it to it's roots as a workaround with 3Gun rules of the '80s that outlawed 5.56 in competition. Well, the .30x5.56 wildcats got tossed out to, as Real Men only shot .30 cal battle rifles back then. Once 5.56 was allowed, guess what. all those Real Men quickly switched to AR15's in 5.56 and moved on. .300 Whisper was developed later by SSK.
Now we get the consumer market involved, and as with ANY non military surplus cartridge, you decide to reload or buy surplus cheaper.
If all that is needed is to pop caps and poke holes in paper or dirt, shoot all the 5.56 or X39 you can get.
If you need a specific recipe of power and range to hit a target, then you specify it, sort out which rounds are the ones that provide it, and live with the choice. It will be the most effective, which strangely enough includes cost of ammo and whether the difference in downrange performance is just incremental. A lot of times the final choices are within 10%. Close enough.
For my AR pistol, I could have chosen 6.8 as I already had magazines galore, but I didn't - I picked 5.56 as the ammo is dirt cheap for plinking.
Enjoyed using it last fall in two hunting seasons as being a pistol it fit firearms and alternative weapons. I mention all that because too often the question comes up "X or Y?" when the real answer might be "Not X or Y" at all.
Frankly, since the run on .22 we get a lot of this, which is another factor. Since the question seems to be about ammo costs, then why pick an expensive commercial round which is likely not ever going to be available surplus? Don't mind me being critical about that, but a lot of us are still waiting for 25c a round 6.8. I chose not to wait as my performance task didn't "need" the extra power. I could use it, yes, but popping caps at targets with an AR takes a lot of cheap ammo to get skill levels up. And commercial loads aren't the ones to pick for that.
I could get 1,000 foot pounds of force out to 60-80 meter with 5.56 for deer hunting, which is a lot further than I can see in woodlands or dense brush where whitetail hide after leaf fall.
Instead of comparing .300 vs x39, spec what you need the ammo to do and then narrow the range of choices. Including costs I would suggest that good ol 5.56 could do the job.