A number of precision rifle companies that I know have started chambering more and more rifles in 6.5 PRC. My impression is that many of them are going out to PRS type shooters and perhaps some hunters.
The 6.5 Creedmoor does very well competitively out to 1,000 yards, with lots of guys saying the 6mm Creedmoor edges it out a little bit.
In essence, it seems like it's being used to push an extra couple hundred feet per second to gain an advantage in wind and drop and also to edge out a little bit more effective practical distance. Again, this is all from the PRS Shooter's perspective (I don't personally hunt, but I've built a couple 6.5 magnum rifles for some hunters out west).
I'm curious to know the effects of increased recoil, restricted magazine capacity, etc. I imagine many of these rifles are going to shooters who are more interested in the ELR game, where targets regularly go 1200 and beyond, who want the advantages of a 6.5mm cartridge but need a little more oomph. As to re-barreling, most shooters in this field re-barrel their rifles frequently and it's just considered a part of the game. When you look at the cost of a quality re-barreling job once a season or so, it's still much behind the costs of travel, lodging, match fees, training, ammo, yearly range fee etc.
That's just what I know of it. Don't know what (if anything) the long range hunting guys are using it for.