^ It's a question worth asking, but the two or three reasons why one doesn't reload are either no time, lack of space, or can't afford to spend the money on the equipment.
If one is going to or wants to own a gun that doesn't shoot .22, 9mm, .40, .38/.357, maybe .45 ACP they would do themselves a favor by reloading. .32 and .45 Colt are what got me into reloading and I find it so easy and rewarding that I bought dies to do .38 and .357, even though I can get factory .38 cheap.
The big bore revolvers are where a lot of money can be saved by reloading and something like .44 Mag, normally stout recoiling, one can load it light to .44 Special levels and make it more enjoyable without having to pay the .44 Special premium.
Same with .327, but .32 S&W Long is quite affordable.
The only cartridges I find aren't worth reloading are 9mm, .40, .357 Sig because either because the ammo is cheap enough to afford or in .357's case, too much time spent prepping the case. About the only auto handgun cartridge I think is worth reloading is 10mm. .45 it depends, if you want to reload a hollow point, it's great, FMJ... eh.