Compressed loads in and of themselves are not a problem.
Improperly-assembled compressed loads are the safety risk, as are any improperly-assembled handloads.
Now, for the uninitiated, the popular Hornady Light Magnum factory ammo is a seriously compressed load that uses a hydraulic ram to really put the squeeze on the powder column. Dangerous? You tell me.
Some powders have a higher load density, and fill a given cartridge case more than others. So you may indeed see a round run out of case capacity before SAAMI pressure limits are reached. Obviously, a compressed charge there is no big deal. My own 6.5-06 runs a compressed load of H4831SC, again, no big deal.
So, let's back off the fear-mongering, and mark the difference between bullet setback (a real problem for spiking chamber pressures) and the compressed loads that have been in reloading manuals and factory ammo since Christ was a corporal.