Recently started carrying an S&W 22-4 as a primary. Not sure why, it is very accurate, uses 6-shot clips which make for surprisingly quick-change cylinder reloads, and I do like the 45 ACP cartridge.
But lets face it, its old tech, sorta like riding an old Norton as opposed to a modern Ninja, both bikes will get you there but the Norton makes for a way more eventful ride. Guess its a time capsule of sorts, taking me back to an age when life was more clear and adventurous.
Bad news if attacked by a half dozen perps, hafta make every shot count.