I've hit a lot of paper plates at 100 yards with ordinary .45 hardball from a 1911. Once you learn the holdover, it's not a big deal.
Flatter shooting happens with lighter bullets, but they also raise the muzzle less by the time they finish traveling down the barrel, so, in a handgun, where barrel whip isn't an issue, they tend to impact lower with the same sight setting to begin with, even at close range. Their shorter time of flight is no guarantee of less wind deflection. The drag component that pulls the bullet away from the wind accelerates a light bullet faster, so it can still end up going just as far to the side or further in that shorter TOF. What really ends up mattering to wind deflection is just the ballistic coefficient of the bullet.
If you are going to change loads for shooting at a longer range, you may want to consider beefing up the velocity of the same bullet or finding a higher ballistic coefficient shape in another bullet nearly the same weight, to avoid creating a short range sight setting difference.
I can think of no reason a wadcutter should become unstable at long range if it was actually stable at short range. Because rotation of a bullet slows down more gradually than forward velocity does, bullets tend to become more stable with range, not less. Only if the bullet is unstable to begin with, does its group spread out with range until it tumbles. If you are seeing bullets become unstable at long range, your barrel is either not spinning them fast enough or you have some other issue (uneven rifling depth at opposite sides of the bore diameter, muzzle crown defect, etc.).
Your wadcutters, at 750 fps, should impact about 2 feet low at 100 yards. For 700 fps, add another 5". It's about twice what my .45 hardball was doing, but neither has anything like the high angled trajectory arc experienced by the guys shooting .45 Colt pistols out to 600 yards or so, trying to hit 8 foot wood target squares. But they do it. Keep an open mind and hold over.