Whitetail Deer. Any number of different rifle choices; I haven't decided yet. I'm gonna change after each deer to a different rifle. After bow season, I'll start out with my Traditions muzzleloader during ML season. Then in gun season, my new Rossi single shot .243 to break it in. Got about 6 or 7 others I'd like to try out. It's gonna depend on how many deer I get a chance at. The new wildlife regs this year are limiting everyone to only 2 bucks per year, from all seasons combined. But you can still get 5 or 6 does in addition, if you do it right, and hunt all the special doe seasons.
Not big game, but for fall turkeys, I'm looking forward to trying my new "ultimate fall turkey gun" out - a Spartan/Baikal SPR94 combo gun in 12 ga / .223 rem.
Then after deer & turkey seasons, I'm going after feral pigs with a Rem 1100 sportsman deer slug gun in 12 ga.