Unique powder is, well, unique.
I haven't found anything nearly so versatile, for so many different uses, as Unique. If I had to use only one powder for all handgun loading, this would be it. Even the "old" Hercules version wasn't as "Dirty" as the rap it gets. Mostly, that had to do with the sooty deposits left by Unique in combination with soft lead bullets and the old, black, Lyman Ideal lubricant. With modern lubes and halfway moderate velocities, most of the "fouling" comes out with a dry brush and a dry patch.
With jacketed or plated bullets, I have no difficulty a-tall.
Some favorite loads with Unique:
9x19 mm 115 jacketed 6.0 gr ~1200 from a Hi Power
" 124 JHP 5.6 gr ~ 1120 Hi Power & a Glock 19 - - close to Speer GDHP factory
.40 S&W 180 JHP 6.2 gr. ~ 900 in a .40 Hi Power
.38 Spl 158 lead 4.5 gr ~ 850 in a 6" Colt OMS.
.357 158 JHP 7.5 gr ~1020 in a 4" S&W M19
You CAN go hotter with other powders but the above are good, solid loads for practice, plinking, and are within published maximums.
These are all the cartridges you mention. I also use Unique in .380, .38 S&W, .41 mag, .44 Spl, .44 mag, .45 ACP, .45 Auto Rim, and .45 Colt.
Best of luck
Johnny