I bought a 22 TR, fairly early in the production run. Early guns had too-tall front sights. My gun shot a foot low, and four inches right, at 25 yards. The factory replacement sight would have raised the POI only six inches, so I did the math, and not trusting math, filed half way, tested, filed half the remaining, etc., in three or four steps, until it was dead-on (the math was right, BTW). I then filed the left side of the sight, bringing windage in line, and creating a bit of light on either side of the sight; the one great weakness of the 22 is the sights. The front sight completely fills the notch, making windage alignment difficult, and the curved upper surface sort of disappears in some light, making precise elevation alignment difficult. A replacement sight, in the form of a post, would be nice, but it would also have to be trimmed to get the gun zeroed.
I've had the Master Action Job performed on my gun, and that included both a smoothing and lightening of the pull, and a chamfering of the charge holes. Reloads were always easy, with roundnosed bullets, but that much easier, now. I always pre-load as many clips as I'm going to need at the range, so I don't have to fiddle with the clips. After loading the gun, I test for both high primers and bent clips by pulling the trigger far enough that the cylinder can free-wheel, then rotating the cylinder through one or two turns. If there's no drag, it's good to go. If a clip is bent, I toss it. Some day I'll get de-mooner, but for now, I use a 1911 barrel to pull the cases off the clip.