You would definitely not be following safe loading recommendations if you loaded 150 grains of loose 777.
Loose 777 loadings should be reduced by about 15% volume to equal loads of other loose ffg powders, especially when shooting 777 fffg due to it's higher pressure. Others have mentioned that their loads start to lose accuracy beyond 120 grains or so of loose 777.
According to Hodgen, loose 777 is more potent than the 777 pellets so you can use less powder to obtain the same velocity (approximately 10 grains or 10% less when comparing the velocity of 80 grains loose 777 to 90 grains of 777 in pellet form):
50 CALIBER POWDER MEASURE SETTING TRIPLE SEVEN FFG (loose powder)
240 Gr. Hdy. XTP 50/44
70 GR. 80 GR. 90 GR. 100 GR.
1633 1703 1806 1883
-----------------
240 Gr. Hdy. XTP 50/44 with pellets
80 grains One 50 cal. / 50 gr. + One 50 cal. / 30 gr. 1613
90 grains Three 50 cal. / 30 gr. 1691
100 grains Two 50 cal. / 50 gr. 1801
Data:
http://www.hodgdon.com/data/muzzlelo...ifle-sabot.php
http://www.hodgdon.com/data/muzzlelo...ts/50sabot.php