Well in the catalog they show the 45 top ends as being diffirent from the 9 / 40 / 357 so yeah to go from 9 to 45 it's going to be some big dollars I would think.
What appealed most to me was the picture of the sub-compact 45 acp --- 6 shot, about the size of sig 239 but 45 acp.
I would only be intrested in this gun if they sell it whole or nearly whole... I have no desire to spend tons of money on a gun only to have to spend hudreds more for add ons....
Honestly the P250 seems to make the most sense for agencies or places like CA where guns are increasinly hard to get so you can have one "frame" and diffirent top ends --- similar to an AR15.