cajun,
The Pow'rBall is NOT a softpoint. It is a plastic ball in the nose. I have shot it in Marcus' CZ 75B (which prompted me to buy my own CZ) into a gel block. I was impressed.
I am not a penetration junkie and I am also not of the opinion that a shallow superficial wound will end a fight. I realize that there is some middle ground. What impressed me was that it was not a sharp round to fire like Fiocchi in 9mm, although the Pow'rBall is +P and Fiocchi is not. Also, the bullet expanded VERY well (flattened out to look like a nickel). It lost some of the jacket along the way and while it went into the 8" or so wide block at a bit of an angle, the force of impact along the way split the side of the block, though the bullet did not exit and was about 2-3" from that particular edge. It may not be my first choice, due to cost, but I would not feel undergunned with it.
I don't think it will go 12+ inches, though. 10-11 may be more like it. However, it should not be impacted nearly as much as some hollow nosed ammo by going through cloth or leather, as it has no cavity to plug.