The problem is two-fold: low peak pressure and light bullet. Both conditions ask for faster powder. The light bullet would be OK at magnum pressures, but not at half that pressure. If I put this powder in QuickLOAD I get very large charge weights and, with a 6" barrel, 40% of the powder is thrown out the muzzle still unburned, so lots of powder flakes will be left in the barrel.
So what, you say. You just want to use the powder up. Well, here's what: I tried this exact same thing with .44 Special in a Charter Bulldog revolver back in the 1980's. The amount of unburned powder flake spread around from between the barrel/cylinder gap was so great it actually jammed the cylinder rotation after a not too many rounds. I had to remove the cylinder and clean it all out in great detail. Way too much bother.
The very old Hornady second edition load manual says that with a 125 grain JHP, they used 11.1 grains to start. Don't trust it. Those old Hornady manual loads were developed in a production gun and never pressure tested. Their starting load for my .44 Special was already at maximum in the light Bulldog. QuickLOAD says its just over SAAMI maximum pressure. 10 grains is a better start number, but don't say Adamantium and I didn't warn you about the dirtiness of it.