I thought that the first book was great but I never bought the others, though I looked through them on many occasions (too bad my local library doesn't carry them, huh?).
I have followed a lot of debate about their methods and findings. I believe the findings but take them with a grain of salt. After all, even they say in the book that SHOT PLACEMENT matters over anything else. It always seems that those who think that their work is crap also disagree with the results (i.e. "my .45 ACP hardball is 95% effective and ain't nobody gonna tell me otherwise"). Drawing the conclusion that their methods and findings are wrong just because they don't agree with what you believe is not really very bright. After all, they did a study and compiled data over the course of time and, even if their findings aren't 100% accurate or their methodology might be questionable, they still DID a study and anyone who wants to refute them probably did NOT...their detractors are probably working totally off of biased opinion rather than fact. Even ER doctors and such aren't a good source of information overall. I guarantee that M&S studied more cases (or, at least, compiled information about more cases) than any ER doctor has ever worked on.
It comes down to this...handguns suck as a killing weapon. In ALL calibers that are used for defense.
Much can be made of wound channels and terminal ballistics and this or that but, when it comes down to it, shooting someone with a handgun round is not a lot different from taking a rounded steel rod of the appropriate diameter and running it into or through someone. It doesn't make a lot of difference whether it is .45" in diameter or .36" in diameter. Handguns rounds don't really have the velocity to damage with their passage like a rifle round (which causes a lot of trauma), so it depends on WHERE they hit a little more. A .22 in the eye is more terminal than a .45 in the pinky toe.
I carry a hi-power with a couple of Mec-Gar magazines that accept 14 rounds instead of 13. With what is chambered, I have 15 rounds in the gun. I really don't care much whether they are ball or hollow-points. I don't feel safer one way or another. I know that, if I have to use it, that I will be shooting multiple times, anyway. I DO carry, at present, a magazine of Black Talons (found a box of them in the back of my gun chest) and a magazine of +P Golden Sabers. Until last weekend, I was carrying all ball and will probably do so again when I shoot up the carry ammo as I rotate it out. I feel fine with any of it. A friend of mine, who has shot people with .45 ACP, 9mm, .223, and .308, says that he feels comfortable with either of the handgun calibers and has never seen a difference like he has with rifle calibers of the damage inflicted when they hit (he carries 9mm now but admits that, psychologically, the .45 ACP makes him feel better to shoot because of his indoctrination in the "fact" that it's the best handgun round).
But I digress...
Everyone can have their opinions but please keep in mind that, unless you've spent years doing a study, that your opinions are probably, at best, no better than the M&S studies and most likely a lot worse.