I never needed to on my M1A.
When it comes to "Loctite" on gun screws it's important to use the right one for what you want. Loctite makes a whole range of products, some of which are meant to be permanent. You don't want to use permanent Loctite on a screw you might need to remove once in a while...
I use a product called "Guntite" (I think its a Loctite product but I don't have the tube handy to check..
) The tube I have (when I find it...) has green lettering on the label, not red or blue, and its made for gun screws. Holds well (never had a screw loosen) and the screws come out normally with the right screwdriver.
The key is to ensure all oil and grease is removed from the threads of both the screw and the screw hole. Then a drop of guntite will hold very well.
Another trick is to use a drop of paint or nail polish so that when dried it overlaps the screwhead and what its screwed into. This holds fairly well, and is also a "tell" that you can see crack if the screw does move.
Staking and the extreme, tack-welding can be done, but I consider that a last resort.