Leupold VX3I 4.5x14x50 B/C retical?

I have this scope mounted on my REM SPS 30-06 both new.I have been watching YouTube videos on both items.One video on the B/C retical on my scope says the bottom lines for 200-300-400 yards are set for a certain factory load and rifle.Im pleasantly sighted in at 100yrds with 150gr core-loks with said equip.Shouldn't the bottom lines be right for my load and equipment if and when I choose to shoot further thanks.
 
While likely they will be very close to impact at those ranges, the only way to know for sure is to test them. Even if you shoot same weight bullet as what they were designed for, doubt they will be "dead on".
 
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