I see two potential problems with what I understand from your question.
The driving bands of the bullets could interfere with fully chambering in some revolvers. The wad cutter is for the most part a cylinder from end to end. Just seat it properly.
Hard cast bullets tend to be a little smaller and lighter. Slug your barrel and try to cast (size to) the proper diameter. Too small and gas will get past with the results of greater leading and loss of velocity. In any case, along with proper sizing, a very good bullet lub will be necessary to reduce leading. Well put together lead loads can run at some very impressive velocities with out leading.
Additionally, I don't truly understand just what you are attempting. I'm not finding fault, to the contrary, I applaud your endeavors. For personal defense, it is your life, go with a suitable jacketed load. For hunting, OK, I would opt for a heavier slug. For practice, why push the load. Yes, the point of impact would be different but practice is practice. Verify your capabilities with the load to be carried.
Enjoy and be safe,
OSOK