If you are interested in 1st year production pythons, #39, LNIB sold for $8,257 in January of this year. Somebody got a steal! I wouldn't have considered parting with a gun like that for less than $13,000.
Thats not really because of the first year status, but more so it was the 39th one, period. Most people have never saw or had one earlier than that. IIRC SNs for first year Pythons went over 500. I would be happy to have say SN 450, and no, it would not bring that kind of money, around half perhaps.
However, I do believe that Python values (accounting for inflation) will fall some over time. The demographics are pushing the value of Pythons. When the Boomers are done buying guns, there won't be as much interest in Pythons.
On the other hand, some baby boomers will buy more guns after they retire and most will have retired in the next 15 years. If you figure the retirement age to be about 65, and add in the fact that people live longer, and 80 years of age is no big deal, the Python prices (using that logic) and Colt DA revolver prices in general could be high for 30 or more years from now before they fall, if they ever do.
IMO some people predicted that Luger prices would fall as soon as the WWII generation passed on, but if anything, there is even more interest than before since original survivors are more and more uncommon. Lugers are more historic, but the theory is the same. Baby boomers do represent a high pct of the population so you might be right, someday far away IMO.