I run Big Game in my .243 and, well, I'm up to my ears in other Ramshot powders I haven't tried yet. I'm very happy with Big Game, like Steve said- it's a ball powder, meters very well, has been quite consistent between lot numbers. I live in West Texas, so I don't know much about temp extremes on powders (32-105 is about all the range I shoot in). I do believe it shoots cleaner than several of the IMR powders I've tried.