Physically, as in length? Yeah, it should fit. And for some bucks, I'm sure somebody could make a barrel. I'm unsure about the effect of firing the 300WSM on the bolt/mechanism, though. I think you'd need stronger parts in there. Then there's the same/similar consideration with the receiver and gas operator.
I do not possess the smarts to do anything other than know where some of the problem areas would be.
Anybody else?