450 is producing accuracy numbers that can only be dreamed of from a 45-70.
What????
There's absolutely no difference in the accuracy potential of these two rounds.
Go visit the Marlin discussion board for multiple examples of submoa 45-70s.
I've shot a 3/4" group using Winchester factory 45-70 and a Thompson Encore rifle.
As for the power difference, I can think of at least three companies off the top of my head that sell 45-70 ammo that equals or surpasses the performance of the single load available for the 450 Marlin.
These two cartridges are ballistic twins. The practical differences are negligible. If you like 450 go for it. If you like 45-70, more power to you.
The only REAL difference I see is that there is only one commercial load available for the 450 Marlin while there is a wide variety of loadings for the 45-70.
Here's some ammo information. Note that Buffalobore Ammo loads a ballistic duplicate of the single available .450 Marlin load.
.450 Marlin
350 grains @ 2150fps Hornady
45-70
300 grains @ 1800fps Federal & Winchester Factory loads
350 grains @ 1800fps CorBon
350 grains @ 2000fps Hunting Shack Ammo
350 grains @ 2050fps PMC Factory Load
350 grains @ 2150 fps Buffalobore Ammunition
400 grains @ 1800 fps Hunting Shack Ammo
405 grains @ 1300fps Remington Factory
405 grains @ 1650fps CorBon
405 grains @ 2000 fps Buffalobore Ammunition
420 grains @ 1850fps Garrett Ammunition
430 grains @ 1925 fps Buffalobore Ammunition
500 grains @ 1625 fps Buffalobore Ammunition
540 grains @ 1550fps Garrett Ammunition