I load my 158 JHP's (Everglades) with 15.0gn of 2400. R-P brass; CCI 500 primers. They run 1291 f/s though a 686 w/ a 4" bbl. It's a good stout round; yet "balanced" without excessive flash and thrust recoil. I've tested them with more charge weight - using both CCI 500 and 550 primers - and got little more performance. Side note: The mag primers yielded no more velocity with more pressure signs, btw. It would seem there is no benefit using mag primers with 2400.
Using Starline brass (which weigh about 5% more than R-P), I'll get cratered primers that stand out proud, locking the cylinder about 10% of the time. Oddly, the Starline ammo yields less velocity (1246 f/s) than the R-P brass ammo. Needless to say, I stick with R-P brass.
Also, either ammo seems to shoot just fine in my Henry carbine (16.5" bbl) with no signs of pressure. But the R-P brass version is still the velocity winner at 1690 f/s vs 1668 f/s.
In my experience, 158 grain bullets with 2400 is the winning combination. I used to use W296; but with lower velocity yields (admittedly, I probably could have worked up the charge weights more). And W296 comes with a huge flame bloom, big booming report, and much higher thrust recoil. The two rounds' (2400 vs W296) shooting characteristics bear no resemblance to one-another. And yet, the one that behaves much more tame, actually yields higher velocity. W296 likely comes into better balance through longer barrels - 4" just isn't enough for it.